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Single-nucleus RNA sequencing reveals that macrophages and smooth muscle cells promote carotid atherosclerosis progression through mitochondrial autophagy

2023-05-31

Abstract excerpt

Objects Carotid atherosclerotic plaques are the manifestation of atherosclerosis in the carotid arteries and can significantly increase the incidence of cerebrovascular disease. Macrophages and smooth muscle cells are crucial for their development. Our research aimed to reveal the mechanism of carotid atherosclerotic plaque formation. Methods The collected carotid plaques were processed to extract RNA and create...

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Literature Corpus work
970374eb-bbf4-51b5-9fc1-8848829921c6
DOI
10.21203/rs.3.rs-2917007/v1
Open publication

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Single-nucleus RNA sequencing reveals that macrophages and smooth muscle cells promote carotid atherosclerosis progression through mitochondrial autophagyDOI 10.21203/rs.3.rs-2917007/v1
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