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Article

Mitochondrial Dysfunction Associated with mtDNA Mutation: Mitochondrial Genome Editing in Atherosclerosis Research.

Current medicinal chemistry - 1 Jan 2026

Khotina Victoria A, Vinokurov Andrey Y, Sinyov Vasily V, Zhuravlev Alexander D, Popov Daniil Y, Sukhorukov Vasily N, Sobenin Igor A, Orekhov Alexander N

Abstract excerpt

BACKGROUND: Atherosclerosis is a complex cardiovascular disease often associated with mitochondrial dysfunction, which can lead to various cellular and metabolic abnormalities. Within the mitochondrial genome, specific mutations have been implicated in contributing to mitochondrial dysfunction. Atherosclerosis-associated m.15059G>A mutation has been of particular interest due to its potential role in altering...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Membrane Potential, Mitochondrial

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Identifiers

PMID: 39400015
DOI: 10.2174/0109298673323639240926095549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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