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Article

Do Mitochondrial DNA Mutations Play a Key Role in the Chronification of Sterile Inflammation? Special Focus on Atherosclerosis.

Current pharmaceutical design - 1 Jan 2021

Orekhov Alexander N, Gerasimova Elena V, Sukhorukov Vasily N, Poznyak Anastasia V, Nikiforov Nikita G

Abstract excerpt

BACKGROUND: The aim of the elucidation of mechanisms implicated in the chronification of inflammation is to shed light on the pathogenesis of disorders that are responsible for the majority of the incidences of diseases and deaths, and also causes of ageing. Atherosclerosis is an example of the most significant inflammatory pathology. The inflammatory response of innate immunity is implicated in the development...

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Identifiers

PMID: 33045961
DOI: 10.2174/1381612826666201012164330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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