Article

Macrophage Autophagy in Atherosclerosis: A Central Regulator of Lipid Metabolism, Inflammation, and Plaque Stability as a Novel Therapeutic Target–A Systematic Review

2026-04-15

Abstract excerpt

<h4>Background: </h4> We systematically evaluated the role of macrophage autophagy in the initiation, progression, and stabilization of atherosclerotic plaques, with particular focus on its effects on lipid metabolism and foam cell formation. Secondary objectives included investigating the relationship between macrophage autophagy and inflammatory responses, selective autophagy processes (such as mitophagy, ferrop...

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Literature Corpus work: efb19869-a0e8-5ff9-a7a9-991041960148
DOI: 10.20944/preprints202604.1032.v1

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