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NFAT5 in cellular adaptation to hypertonic stress – regulations and functional significance

23 Apr 2013

Abstract excerpt

The Nuclear Factor of Activated T Cells-5 (NFAT5), also known as OREBP or TonEBP, is a member of the nuclear factors of the activated T cells family of transcription factors. It is also the only known tonicity-regulated transcription factor in mammals. NFAT5 was initially known for its role in the hypertonic kidney inner medulla for orchestrating a genetic program to restore the cellular homeostasis. Emerging...

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PMID: 23618372
DOI: 10.1186/1750-2187-8-5

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NFAT5 in cellular adaptation to hypertonic stress – regulations and functional significancePMID 23618372Read ↗

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