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Differences in chromatin accessibility between renal cortex and inner medulla correlate with spatial differences in gene expression and are modulated by NFAT5 function

2024-04-26

Abstract excerpt

<h4>ABSTRACT</h4> A spatial gene expression pattern between the cortex (CTX) and inner medulla (IM) of the kidney has been observed, but the underlying mechanisms are unclear. Understanding these mechanisms is essential for elucidating renal function. Using the Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq) we analyzed the open chromatin structures and the involvement of epi...

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Literature Corpus work
fe796286-819b-5857-a106-0c7f88d6dabd
DOI
10.1101/2024.04.23.589187
Open publication

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Differences in chromatin accessibility between renal cortex and inner medulla correlate with spatial differences in gene expression and are modulated by NFAT5 functionDOI 10.1101/2024.04.23.589187
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