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Article

RNA-Seq analysis of high NaCl-induced gene expression.

Physiological genomics - 1 Oct 2015

Izumi Yuichiro, Yang Wenjing, Zhu Jun, Burg Maurice B, Ferraris Joan D

Abstract excerpt

High extracellular NaCl is known to change expression of numerous genes, many of which are regulated by the osmoprotective transcription factor nuclear factor of activated T cells-5 (NFAT5). In the present study we employed RNA-Seq to provide a comprehensive, unbiased account of genes regulated by high NaCl in mouse embryonic fibroblast cells (MEFs). To identify genes regulated by NFAT5 we compared wild-type MEFs...

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Source

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Identifiers

PMID: 26220925
DOI: 10.1152/physiolgenomics.00057.2015
PMCID: PMC4593828

Genes

NFAT5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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