Article

Single nuclei/cell transcriptomics reveal DMD driven cell dynamics and mechanisms of fibroblast inflammatory tissue priming in human dystrophic muscle

2026-04-08

Abstract excerpt

<title>Abstract</title> <p>Single cell/nuclei technologies have revolutionized our understanding of the remodeling of complex multi-cellular tissue that accompanies injury, regeneration, and disease. Duchenne muscular dystrophy (DMD) is a fatal genetic disease of childhood characterized by progressive skeletal muscle weakness resulting from mutation of DMD and loss of functional dystrophin. Here we report, at sin...

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Literature Corpus work: 48be8f69-deba-5522-a439-16ba1c01c522
DOI: 10.21203/rs.3.rs-4934147/v1

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