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Article

A cellular and molecular spatial atlas of dystrophic muscle

6 Jul 2023

Abstract excerpt

Asynchronous skeletal muscle degeneration/regeneration is a hallmark feature of Duchenne muscular dystrophy (DMD); however, traditional -omics technologies that lack spatial context make it difficult to study the biological mechanisms of how asynchronous regeneration contributes to disease progression. Here, using the severely dystrophic D2-mdx mouse model, we generated a high-resolution cellular and molecular...

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PMID: 37410813
DOI: 10.1073/pnas.2221249120

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