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Single cell RNA sequencing of human FAPs reveals different functional stages in Duchenne muscular dystrophy

9 Jul 2024

Abstract excerpt

Background: Duchenne muscular dystrophy is a genetic disease produced by mutations in the dystrophin gene characterized by early onset muscle weakness leading to severe and irreversible disability. Muscle degeneration involves a complex interplay between multiple cell lineages spatially located within areas of damage, termed the degenerative niche, including inflammatory cells, satellite cells (SCs) and...

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PMID: 39045456
DOI: 10.3389/fcell.2024.1399319

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