Article

A modified methyl transferase cofactor to selectively disable gene expression in <i>E. coli</i>

2025-04-10

Abstract excerpt

Artificial control of gene expression in bacteria offers interesting prospects for influencing bacterial pathogenicity and antibiotic resistance. We show that the methyl-transferase cofactor, AdoHcy azide, can disable gene expression in modified plasmids in some strains of E. coli , where ampicillin and kanamycin resistance as well as eGFP genes were selectively and independently disabled. The disabling of transc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 488f3631-dfbb-50a9-8bf1-44e31700833d
DOI: 10.1101/2025.04.10.648196

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A modified methyl transferase cofactor to selectively disable gene expression in <i>E. coli</i>DOI 10.1101/2025.04.10.648196Read

Dynamics and quantitative contribution of the aminoglycoside 6′- <i>N</i> -acetyltransferase type Ib [AAC(6′)-Ib] to amikacin resistanceSemantic proximity Read

One-for-all gene inactivation via PAM-independent base editing in bacteriaSemantic proximity Read

Functional genomics reveals extensive diversity in <i>Staphylococcus epidermidis</i> restriction modification systems compared to <i>Staphylococcus aureus</i>Semantic proximity Read

DNA methyltransferase enhanced <i>Fusobacterium nucleatum</i> geneticsSemantic proximity Read

Interrogating the <i>Escherichia coli</i> epitranscriptome via CRISPR interference and Nanopore native RNA sequencingSemantic proximity Read

Efficient genetic code expansion tools enable <i>in vivo</i> study of lysine acetylation in non-model bacteriaSemantic proximity Read

SyngenicDNA: stealth-based evasion of restriction-modification barriers during bacterial genetic engineeringSemantic proximity Read

Role of DNA methyltransferases in epigenetic regulation in bacteria.Semantic proximity Read

General Transcription Factor from <i>E. coli</i> with a Distinct Mechanism of ActionSemantic proximity Read

Equip <i>Fusobacterium nucleatum</i> genetic tool kits with compatible shuttle vectors and engineered intermediatory <i>E. coli</i> strains for enhanced transformation efficiencySemantic proximity Read

The dam and dcm strains of Escherichia coli--a review.Semantic proximity Read

Purging the transcriptome for antibiotic tolerance.Semantic proximity Read