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Dynamics and quantitative contribution of the aminoglycoside 6′- <i>N</i> -acetyltransferase type Ib [AAC(6′)-Ib] to amikacin resistance

2023-09-07

Abstract excerpt

Aminoglycosides are essential components in the available armamentarium to treat bacterial infections. The surge and rapid dissemination of resistance genes strongly reduce their efficiency, compromising public health. Among the multitude of modifying enzymes that confer resistance to aminoglycosides, the aminoglycoside acetyltransferase AAC(6′)-Ib is the most prevalent and relevant in the clinical setting as it c...

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Literature Corpus work
c446e64b-2cb2-5263-8658-5cbae3cd9bd1
DOI
10.1101/2023.09.05.556435
Open publication

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