Article

Efficient genetic code expansion tools enable <i>in vivo</i> study of lysine acetylation in non-model bacteria

2025-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Recent proteomic advancements have revealed widespread Nε-lysine acetylation in pathways governing pathogenicity, metabolism, and antibiotic resistance in bacteria. The spontaneous, non-specific nature of this modification in prokaryotes obscures its biological role, necessitating prokaryotic specific in vivo interrogation systems. Genetic Code Expansion (GCE) offers a powerful method to invest...

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Literature Corpus work: b2944d59-13c1-55bb-8de6-6f7d14e79e95
DOI: 10.1101/2025.04.14.648644

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