Article

DNA methyltransferase enhanced <i>Fusobacterium nucleatum</i> genetics

2022-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial restriction-modification (R-M) systems are a first line immune defense against foreign DNA from viruses and other bacteria. While R-M systems are critical in maintaining genome integrity, R-M nucleases unfortunately present significant barriers to targeted genetic modification. Bacteria of the genus Fusobacterium are oral, Gram-negative, anaerobic, opportunistic pathogens that are imp...

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Literature Corpus work: 10ebf13c-be01-5fd7-9c84-f8176fe3fba0
DOI: 10.1101/2022.07.20.500824

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