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Article

The dam and dcm strains of Escherichia coli--a review.

Gene - 27 May 1994

Palmer B R, Marinus M G

Abstract excerpt

The construction of a variety of strains deficient in the methylation of adenine and cytosine residues in DNA by the methyltransferases (MTases) Dam and Dcm has allowed the study of the role of these enzymes in the biology of Escherichia coli. Dam methylation has been shown to play a role in coordinating DNA replication initiation, DNA mismatch repair and the regulation of expression of some genes. The regulation...

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PMID: 8200522
DOI: 10.1016/0378-1119(94)90597-5

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