Article

ADR-2 regulates fertility and oocyte fate in <i>C. elegans</i>

2023-11-02

Abstract excerpt

RNA binding proteins play essential roles in coordinating germline gene expression and development in all organisms. Here, we report that loss of ADR-2, a member of the Adenosine DeAminase acting on RNA (ADAR) family of RNA binding proteins and the sole adenosine-to-inosine RNA editing enzyme in C. elegans , can improve fertility in multiple genetic backgrounds. First, we show that loss of RNA editing by ADR-2 re...

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Literature Corpus work: 4991155e-d607-58bf-96e9-b53ace38d7c4
DOI: 10.1101/2023.11.01.565157

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