Article

A cytoplasmic Argonaute protein promotes the inheritance of RNAi

2017-12-17

Abstract excerpt

<h4>Summary</h4> RNAi-elicited gene silencing is heritable and can persist for multiple generations after its initial induction in C. elegans . However, the mechanism by which parental-acquired trait-specific information from RNAi is inherited by the progenies is not fully understood. Here, we identified a cytoplasmic Argonaute protein, WAGO-4, necessary for the inheritance of RNAi. WAGO-4 exhibits asymmetrical...

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Literature Corpus work: da9de0a7-41e4-5bd6-91a9-cdd41fb0557a
DOI: 10.1101/235713

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