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Article

The CSR-1 endogenous RNAi pathway ensures accurate transcriptional reprogramming during the oocyte-to-embryo transition in Caenorhabditis elegans.

PLoS genetics - 1 Mar 2018

Fassnacht Christina, Tocchini Cristina, Kumari Pooja, Gaidatzis Dimos, Stadler Michael B, Ciosk Rafal

Abstract excerpt

Endogenous RNAi (endoRNAi) is a conserved mechanism for fine-tuning gene expression. In the nematode Caenorhabditis elegans, several endoRNAi pathways are required for the successful development of reproductive cells. The CSR-1 endoRNAi pathway promotes germ cell development, primarily by facilitating the expression of germline genes. In this study, we report a novel function for the CSR-1 pathway in preventing...

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Identifiers

PMID: 29579041
DOI: 10.1371/journal.pgen.1007252
PMCID: PMC5886687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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