Article

Genetic liability to metabolic dysfunction modelled in early adulthood predicts cardiometabolic risk across the life course in Asian populations

2026-04-27

Abstract excerpt

<h4>Background</h4> Cardiometabolic diseases arise from metabolic dysfunction that develops decades before clinical onset. Conventional genetic risk models are typically derived in middle-aged or older populations, where genetic effects are confounded by cumulative environmental exposures, chronic comorbidities, and clinical interventions. Whether the life stage at which genetic liability is modelled influences t...

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Literature Corpus work: 4815c320-9376-5819-b376-2375954de880
DOI: 10.64898/2026.04.24.26351660

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