Article
Polygenic Risk Scores for Cardio-renal-metabolic Diseases in the Penn Medicine Biobank
2019-09-08
Abstract excerpt
Cardio-renal-metabolic (CaReMe) conditions are common and the leading cause of mortality around the world. Genome-wide association studies have shown that these diseases are polygenic and share many genetic risk factors. Identifying individuals at high genetic risk will allow us to target prevention and treatment strategies. Polygenic risk scores (PRS) are aggregate weighted counts that can demonstrate an individu...
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Identifiers and source
- Literature Corpus work
- 09daed90-9807-53d3-a509-e2e652e59d14
- DOI
- 10.1101/759381