Article
Associations of metabolic changes and polygenic risk scores with cardiovascular outcomes and all-cause mortality across BMI categories: a prospective cohort study.
Cardiovascular diabetology - 4 Jul 2024
Li Cancan, Meng Xiaoni, Zhang Jie, Wang Haotian, Lu Huimin, Cao Meiling, Sun Shengzhi, Wang Youxin
Abstract excerpt
BACKGROUND: Associations between metabolic status and metabolic changes with the risk of cardiovascular outcomes have been reported. However, the role of genetic susceptibility underlying these associations remains unexplored. We aimed to examine how metabolic status, metabolic transitions, and genetic susceptibility collectively impact cardiovascular outcomes and all-cause mortality across diverse body mass...
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