Article

Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia

2021-08-06

Abstract excerpt

<h4>Background & Aims</h4> The c-Myc (Myc) bHLH-ZIP transcription factor is deregulated in most cancers. In association with Max, Myc controls target genes that supervise metabolism, ribosome biogenesis, translation and proliferation. This “Myc Network” cross-talks with the “Mlx Network”, which consists of the Myc-like proteins MondoA and ChREBP and Max-like Mlx. Together, this “Extended Myc Network” regulates bo...

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Literature Corpus work: 47fa7741-aedf-5ba0-8e93-0dc800ff65b8
DOI: 10.1101/2021.08.05.455215

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