Article
Extrachromosomal Circular DNA Orchestrates Genome Heterogeneity and Outcome in Urothelial Bladder Carcinoma
2023-03-03
Abstract excerpt
<title>Abstract</title> <p>Extrachromosomal circular DNA (circulome) is a newly evolved hallmark in cancer whereas its role in shaping the cancer genome heterogeneity is yet to be sufficiently understood. Here, we comprehensively characterize and exploit the circulome-associated genome heterogeneity in 80 urothelial bladder carcinoma (UBC) patients by whole-genome/exome sequencing, Circle-Seq, long-read sequencin...
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Identifiers and source
- Literature Corpus work
- 472a6ad4-6d97-5ad5-996a-7024dad859ae
- DOI
- 10.21203/rs.3.rs-2169951/v1