Article

Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency

2024-02-29

Abstract excerpt

Nuclear speckles, a type of membraneless nuclear organelle in higher eukaryotic cells, play a vital role in gene expression regulation. Using the reverse transcription-based RNA-binding protein binding sites sequencing (ARTR-seq) method, we study human transcripts associated with nuclear speckles. We identify three gene groups whose transcripts demonstrate different speckle localization properties and dynamics: st...

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Literature Corpus work: 4717afb3-0ce6-5da6-ac12-010c334c4ca2
DOI: 10.1101/2024.02.29.581881

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