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Article

The ISWI chromatin remodeler organizes the hsrω ncRNA-containing omega speckle nuclear compartments.

PLoS genetics - 1 May 2011

Onorati Maria C, Lazzaro Sandra, Mallik Moushami, Ingrassia Antonia M R, Carreca Anna P, Singh Anand K, Chaturvedi Deo Prakash, Lakhotia Subhash C, Corona Davide F V

Abstract excerpt

The complexity in composition and function of the eukaryotic nucleus is achieved through its organization in specialized nuclear compartments. The Drosophila chromatin remodeling ATPase ISWI plays evolutionarily conserved roles in chromatin organization. Interestingly, ISWI genetically interacts with the hsrω gene, encoding multiple non-coding RNAs (ncRNA) essential, among other functions, for the assembly and...

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PMID: 21637796
DOI: 10.1371/journal.pgen.1002096
PMCID: PMC3102753

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