Article

Disentangling spatial organization and splicing of rare intron classes in the human genome

2025-08-15

Abstract excerpt

Three-dimensional (3D) genome organization influences transcription and RNA processing, yet how the spatial positioning of genes contributes to pre-mRNA splicing has only recently come into focus. Despite these advances, it remains unclear how introns, particularly rare intron classes, are organized within the 3D genome and whether this organization influences their splicing. Here, we mapped the spatial organizati...

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Literature Corpus work: 48718fb8-b851-5bff-96ab-cbe836faeb48
DOI: 10.1101/2025.08.11.669784

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