Article

RNA localization to nuclear speckles follows splicing logic

2025-05-28

Abstract excerpt

<h4>Summary</h4> Nuclear speckles are membraneless organelles implicated in multiple RNA processing steps. In this work, we systematically characterize the sequence logic determining RNA localization to nuclear speckles. We find extensive similarities between the speckle localization code and the RNA splicing code, even for transcripts that do not undergo splicing. Specifically, speckle localization is enhanced b...

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Literature Corpus work: 3bbae0dd-80fe-5207-bc89-e77151d2449a
DOI: 10.1101/2025.05.28.656493

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