Article

MR1-restricted T cell clonotypes are associated with ‘resistance’ to <i>M.tuberculosis</i> infection

2022-10-13

Abstract excerpt

<h4>ABSTRACT</h4> T cells are required for a protective immune response against the human adapted pathogen Mycobacterium tuberculosis (M.tb). We recently described a cohort of Ugandan household contacts of tuberculosis cases that appear to ‘resist’ M.tb infection (RSTRs) and showed that these individuals harbor IFN-γ independent T cell responses to M.tb-specific peptide antigens. However, T cells also recognize...

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Literature Corpus work: 470266c6-472c-5521-bead-7fc10b1b9cef
DOI: 10.1101/2022.10.12.511825

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