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Human CD1c-autoreactive T-cells recognise <i>Mycobacterium tuberculosis</i> –infected antigen-presenting cells and display cytotoxic effector programmes

2026-01-20

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains the leading cause of death from infection globally, yet the contribution of non-classical T-cell pathways to human immunity remains poorly defined. CD1c-autoreactive T-cells, which recognise self-lipids presented by the antigen-presenting molecule CD1c, are frequent in human blood, but their role during infection is unclear. Here, we investiga...

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Literature Corpus work
a143e7ca-38c9-5061-935f-ed0578026d0c
DOI
10.64898/2026.01.16.700025
Open publication

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Human CD1c-autoreactive T-cells recognise <i>Mycobacterium tuberculosis</i> –infected antigen-presenting cells and display cytotoxic effector programmesDOI 10.64898/2026.01.16.700025
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