Article

Rare Variable <i>M. tuberculosis</i> Antigens induce predominant Th17 responses in human infection

2024-03-06

Abstract excerpt

CD4 T cells are essential for immunity to M. tuberculosis ( Mtb ), and emerging evidence indicates that IL-17-producing Th17 cells contribute to immunity to Mtb . While identifying protective T cell effector functions is important for TB vaccine design, T cell antigen specificity is also likely to be important. To identify antigens that induce protective immunity, we reasoned that as in other pathogens, effecti...

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Literature Corpus work: f6f191d6-7e31-5f5a-9e67-6e3bd5caf6b8
DOI: 10.1101/2024.03.05.583634

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