Article

Unbiased definition of a shared T-cell receptor motif enables population-based studies of tuberculosis

2017-04-03

Abstract excerpt

<h4>ABSTRACT</h4> Peptide-specific T cells that are restricted by highly polymorphic major histocompatibility complex (MHC) proteins express diverse T-cell receptors (TCRs) that are rarely shared among unrelated individuals. T-cells can also recognize bacterial lipid antigens that bind the relatively non-polymorphic CD1 family of proteins. However, genetic variation in human CD1 genes and TCR diversity expressed...

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Literature Corpus work: b57c9e4e-e5c1-5e6a-a4f0-98eea6ee0241
DOI: 10.1101/123174

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