Article
SomaticSiMu: a mutational signature simulator.
Bioinformatics (Oxford, England) - 28 Apr 2022
Chen David, Randhawa Gurjit S, Soltysiak Maximillian P M, de Souza Camila P E, Kari Lila, Singh Shiva M, Hill Kathleen A
Abstract excerpt
SUMMARY: SomaticSiMu is an in silico simulator of single and double base substitutions, and single base insertions and deletions in an input genomic sequence to mimic mutational signatures. SomaticSiMu outputs simulated DNA sequences and mutational catalogues with imposed mutational signatures. The tool is the first mutational signature simulator featuring a graphical user interface, control of mutation rates and...
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