Article

FUS binding to RNA prevents R-loops

2022-08-12

Abstract excerpt

<h4>ABSTRACT</h4> The protein FUS (FUSed in sarcoma) is a metazoan RNA-binding protein that influences RNA production by all three nuclear polymerases. FUS also binds nascent transcripts, RNA processing factors, RNA polymerases, and transcription machinery. We explored the role of FUS binding interactions for activity during transcription. In vitro run-off transcription assays revealed FUS enhanced RNA produced...

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Literature Corpus work: 46307df7-fdfe-5f59-a2f8-65dbd4406dd5
DOI: 10.1101/2022.08.11.503633

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