Article

Transcription factors interact with RNA to regulate genes

2022-09-28

Abstract excerpt

<h4>Summary</h4> Transcription factors (TFs) orchestrate the gene expression programs that define each cell’s identity. The canonical TF accomplishes this with two domains, one that binds specific DNA sequences and the other that binds protein coactivators or corepressors. We find that at least half of TFs also bind RNA, doing so through a previously unrecognized domain with sequence and functional features analo...

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Literature Corpus work: cc0d7a54-5471-5997-a574-5abf51a1f28d
DOI: 10.1101/2022.09.27.509776

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