Article

Effect sizes of somatic mutations in cancer

2017-12-06

Abstract excerpt

<h4>ABSTRACT</h4> A major goal of cancer biology is determination of the relative importance of the genomic alterations that confer selective advantage to cancer cells. Tumor sequence surveys have frequently ranked the importance of substitutions to cancer growth by P value or a false-discovery conversion thereof. However, P values are thresholds for belief, not metrics of effect. Their frequent misuse as metri...

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Literature Corpus work: 45636dc7-9740-5b21-a66e-0d50f72a8055
DOI: 10.1101/229724

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