Article

Synthetic cell-based tissues for bottom-up assembly of artificial lymphatic organs

2024-10-02

Abstract excerpt

Synthetic cells have emerged as novel biomimetic materials for studying fundamental cellular functions and enabling new therapeutic approaches. However, replicating the structure and function of complete tissues as self-organized 3D collectives has remained challenging. Here, we engineer lymph node-mimicking 3D lymphatic bottom-up tissues (lymphBUTs) with mechanical adaptability, metabolic activity, and hierarchic...

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Literature Corpus work: 453a4d35-af0d-55a9-9b1d-8a3675c9ce32
DOI: 10.1101/2024.10.01.616088

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