Multi-trait analysis of gene-by-environment interactions in large-scale genetic studies.

Abstract excerpt

Identifying genotype-by-environment interaction (GEI) is challenging because the GEI analysis generally has low power. Large-scale consortium-based studies are ultimately needed to achieve adequate power for identifying GEI. We introduce Multi-Trait Analysis of Gene-Environment Interactions (MTAGEI), a powerful, robust, and computationally efficient framework to test gene-environment interactions on multiple...

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• Computer Simulation
• Gene-Environment Interaction
• Genome-Wide Association Study
• Phenotype