Article

Cross-species single-cell atlases chart progression, therapy-driven remodelling and immune evasion in pancreatic cancer

2026-03-23

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at advanced stages, yet single-cell datasets that capture late-stage and treated disease remain sparse, hindering progress in understanding tumour heterogeneity and therapy resistance. Here, we have generated integrated single-cell transcriptomic atlases of human and mouse PDAC to define the cellular and molecular landscape of the disease, from early t...

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Literature Corpus work: 44b16973-f2b8-5fcf-8c4f-ff603ca06cb4
DOI: 10.64898/2026.03.19.712924

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