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PDAC tumor Immune system escape architecture: Analysis of transcriptomics of mechanisms that TME is tackling immune system in Pancreatic Ductal Adenocarcinoma Tumors

2025-09-21

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) evolves within a complex tumor microenvironment (TME) that promotes immune evasion and stromal reprogramming characterized by heterogeneous clonal architecture and frequent resistance to apoptosis [1,2,12]. Here, we performed analysis on single-cell RNA sequencing data from 79,409 cells isolated from the pancreas of PDAC patients to dissect intra-tumoral heterogeneity, mecha...

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Literature Corpus work
d88c0320-526c-5035-82c7-b4ec42427f69
DOI
10.1101/2025.09.18.677181
Open publication

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PDAC tumor Immune system escape architecture: Analysis of transcriptomics of mechanisms that TME is tackling immune system in Pancreatic Ductal Adenocarcinoma TumorsDOI 10.1101/2025.09.18.677181
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