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The Diverse Applications of Pancreatic Ductal Adenocarcinoma Organoids

4 Oct 2021

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies. While immortalized cancer cell lines and genetically engineered murine models have increased our understanding of PDAC tumorigenesis, they do not recapitulate inter- and intra-patient heterogeneity. PDAC patient derived organoid (PDO) biobanks have overcome this hurdle, and provide an opportunity for the high throughput...

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PMID: 34638463
DOI: 10.3390/cancers13194979

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