Article

The SpliZ generalizes “Percent Spliced In” to reveal regulated splicing at single-cell resolution

2020-11-11

Abstract excerpt

To date, detecting robust single-cell-regulated splicing is viewed as out of reach from droplet based technologies such as 10x Chromium. This prevents the discovery of single-cell-regulated splicing in rare cell types or those that are difficult or impossible to sequence deeply. Here, we introduce a novel, robust, and computationally efficient set of statistics, the Splicing Z Score (SpliZ) and SpliZVD, to detect...

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Literature Corpus work: 44971527-f57a-543e-8925-32cb8856da08
DOI: 10.1101/2020.11.10.377572

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