Article

Dissimilar conservation pattern in hepatitis C virus mutant spectra, consensus sequences, and data banks

2020-07-03

Abstract excerpt

The influence of quasispecies dynamics on long-term virus diversification in nature is a largely unexplored question. Specifically, whether intra-host nucleotide and amino acid variation in quasispecies fits variation observed in consensus sequences or data bank alignments is unknown. Genome conservation and dynamics simulations are used for the computational design of universal vaccines, therapeutic antibodies an...

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Literature Corpus work: 4475074e-6e08-590f-810b-c2c669f3d0db
DOI: 10.1101/2020.07.03.186171

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