Article

Physical models of spatial genome organization

2016-11-25

Abstract excerpt

<h4>ABSTRACT</h4> Remodeling of nuclear organization occurs during normal cell development, differentiation and cancer. One of the biggest gaps of knowledge remains how to link the information on chromatin and chromosome structural organization with genes activity. In this paper we introduce some physical ideas and a general computational method demonstrating how genome 3D architecture and its remodeling can be q...

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Literature Corpus work: 2a69bf8f-7dfb-526c-9cfb-7a7e1378fa7e
DOI: 10.1101/089755

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