Article
Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism.
Nature communications - 21 May 2015
Ugrankar Rupali, Berglund Eric, Akdemir Fatih, Tran Christopher, Kim Min Soo, Noh Jungsik, Schneider Rebekka, Ebert Benjamin, Graff Jonathan M
Abstract excerpt
Circulating carbohydrates are an essential energy source, perturbations in which are pathognomonic of various diseases, diabetes being the most prevalent. Yet many of the genes underlying diabetes and its characteristic hyperglycaemia remain elusive. Here we use physiological and genetic interrogations in D. melanogaster to uncover the 'glucome', the complete set of genes involved in glucose regulation in flies....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
