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Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection

27 Sept 2021

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus associated with several human cancers. KSHV infection and KSHV-induced anabolic cell proliferation and cellular transformation depend on reprogramming of cellular metabolic pathways, which provide the building blocks and energy for the growth of both the virus and the infected cells. Furthermore, KSHV dysregulates numerous metabolic...

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PMID: 34579773
DOI: 10.1186/s13578-021-00688-0

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