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Transcriptome and chromatin accessibility mapping reveals a type I Interferon response triggered by <i>Mycobacterium tuberculosis</i> infection

2022-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Tuberculosis, a deadly infectious lung disease caused by Mycobacterium tuberculosis (Mtb), remains the leading cause of bacterial disease-related deaths worldwide. The success of Mtb as a human pathogen depends on its ability to manipulate host immune response pathways, many of which are regulated by epigenetic mechanisms that control the accessibility of chromatin to the transcriptional machin...

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Literature Corpus work
4401550a-24ef-5559-a504-492d63c72a75
DOI
10.1101/2022.08.11.503537
Open publication

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Transcriptome and chromatin accessibility mapping reveals a type I Interferon response triggered by <i>Mycobacterium tuberculosis</i> infectionDOI 10.1101/2022.08.11.503537
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