Article
Surveying the Epigenetic Landscape of Tuberculosis in Alveolar Macrophages
21 Mar 2022
Abstract excerpt
, small-animal, or blood-derived cell models, which do not accurately reflect the pulmonary nature of the disease. In humans, the first and major target cells of Mycobacterium tuberculosis are alveolar macrophages (AM). As such, their response to infection and treatment is clinically relevant and ultimately drives the outcome of disease. In this review, we compare the fundamental differences between AM and...
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