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Article

The Role of Epigenetics in Tuberculosis Infection

1 Apr 2016

Abstract excerpt

Epigenetic mechanisms are pivotal in regulating gene expression during cellular response to extracellular stimuli. Bacterial infections have a profound effect on the host epigenome, which triggers susceptibility to diseases. Recent studies suggest that Mycobacterium tuberculosis (Mtb) can alter the host epigenome to modulate the transcriptional machinery and plays a major role in immunomodulation of the host...

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Identifiers

PMID: 27035266
DOI: 10.2217/epi.16.1

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