Article

Deletion of Mcpip1 in Mcpip1 <sup>AlbKO</sup> mice recapitulates the phenotype of human primary biliary cholangitis

2020-09-05

Abstract excerpt

<h4>Background & Aims</h4> Primary biliary cholangitis (PBC) is an autoimmune disease characterized by progressive destruction of the intrahepatic bile ducts. The immunopathology of PBC involves excessive inflammation; therefore, negative regulators of inflammatory response, such as Monocyte Chemoattractant Protein-1-Induced Protein-1 (MCPIP1, alias Regnase1) may play important roles in the development of PBC. T...

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Literature Corpus work: 43f02f63-058f-5c52-a35e-0ec38a5a7898
DOI: 10.1101/2020.09.05.250522

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