Article

Multi-Omics Analysis Reveals Potential Therapeutic Targets and Genetic Mechanisms in Primary Biliary Cholangitis

2025-08-11

Abstract excerpt

<title>Abstract</title> <p>Background Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease with limited treatment options. This study employs multi-omics approaches to investigate its genetic mechanisms and identify potential therapeutic targets. Methods We performed univariable and multivariable Mendelian Randomization (MR) analyses using GWAS datasets to assess methylation, gene expression, a...

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Literature Corpus work: 9b8c06b7-0656-51e0-9398-9fdfbb39491f
DOI: 10.21203/rs.3.rs-7186861/v1

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